Ingredients

Niacin

Niacin or vitamin B3 is a micronutrient that humans cannot make on their own but needs to be supplemented. Niacin is a well-known vitamin with established health benefits such as the normal functioning of the nervous system. Niacin also reduces tiredness and fatigue. Recently it was shown that niacin supplementation in humans improved the available NAD+ levels and had a beneficial impact on the overall body composition, reducing fat.

Resveratrol

Resveratrol is a phytochemical and polyphenol that is naturally occurring in the skin of red grapes, blueberries as well as in dark chocolate. Research suggests that resveratrol is an activator of the sirtuins. Laboratory mice fed with resveratrol had a prolonged life compared to those of the control group and were more active and generally in better shape.

Vitamin D3

Vitamin D3 is a powerhouse molecule and best known for its role in calcium absorption by the body. However, researchers found that vitamin D3 does much more than that. Vitamin D3 also contributes to the normal function of the immune system and has a role in cell division. Scientific research indicates an association between low levels of vitamin D3 and diseases associated with ageing such as cognitive decline, depression, osteoporosis, cardiovascular disease, hypertension, type 2 diabetes, and cancer. Vitamin D3 deficiency was recently linked to the gravity of symptoms in covid-19 patients.

Pomegranate extract

Pomegranate extract contains ellagitannins, which are precursors of Urolithin A. Bacteria in the gut transform the ellagitannins into Urolithin A, which is a compound that is known to positively influence the mitochondria in our cells. The mitochondria are the energy factories of our cells, contributing to the production of ATP, the energy source of our cells. As we age, mitochondrial activity declines, leading to cell damage. Pomegranate extract may help to enforce the mitochondria. In addition, pomegranate extract also comprises punicalagin, a compound linked to the prevention of collagen degradation. As collagen is crucial for delaying skin ageing, pomegranate extract thus also enforces healthy, younger looking skin.

Broccoli Sprouts

Broccoli Sprouts are a source of sulphoraphane which are known to activate the stress-response pathway NRF2 in the human body. NRF2 controls over 200 genes responsible for anti-inflammatory and antioxidant processes. The NRF2 pathway helps the body to suppress inflammation, activates detoxification and promotes antioxidants. Suppression of inflammation in the body is believed to be linked to longevity. Sulphoraphanes the activators of NRF2 have been shown to slow the rate of cancer and cardiovascular problems, as well as play a role in the removal of toxins from our body.

Vitamin K

Vitamin K is an often ignored but important micronutrient. Studies show that Vitamin K supplementation can have a beneficial effect on the maintenance of bones and on diseases linked to ageing, such as osteoarthritis, rheumatoid arthritis and cardiovascular diseases. In addition, vitamin K may affect mitochondrial health.

Betaine / Trimethylglycine

Betaine, also known as Trimethylglycine is a molecule related to choline. Each molecule contains three methyl groups (hence the name trimethyl). Betaine contributes to normal homocysteine metabolism.* Betain/Trimethylglycine assists in methylation of proteins, including the histones. Research suggests a positive influence of TMG on liver detoxification. In addition, TMG also aids in the conversion of homocysteine to methionine. High levels of homocysteine, have been linked to an increased risk of heart disease, heart attack, stroke, Alzheimer’s disease, Parkinson’s disease, and osteoporosis. Through its activity as methyl donor, TMG may further ensure that the methyl pool in our body stays optimal, especially when supplementing with niacin, known to be a methyl consumer.

* the beneficial effect is obtained with a daily intake of 1,5 g of betaine. A daily intake in excess of 4 g may significantly increase blood cholesterol levels